PHYCO-BIOTECH

To find solutions for health issues by using scientific methods to develop and optimize the natural properties of microalgae in collaboration with recognized scientific experts and health professionals.

Phyco-Biotech’s R&D teams have acquired unique expertise in the following processes:

• Extraction and purification of phycobiliproteins to develop fluorescent markers for medical diagnosis, 
• Purification, concentration and freeze-drying of C-phycocyanin for preventive health applications
• Metabolization of trace elements valued for their natural health applications: clinical and sports nutrition, human and animal nutraceuticals, nutricosmetics

• Organic silicon
• Organic selenium
• Organic chromium
• Organic iron
• Organic iodine
• Freeze-dried C-phycocyanin (purified to 93%)

The products developed by Phyco-Biotech capitalize on the results of Research & Development collaboration between our researchers and our scientific partners.

1 in vitro study:

Availability of iron in iron-enriched spirulina using an in vitro digestion/Caco-2 cell culture model

2 preclinical trials:

• Glutathion-related enzymatic activities in rats fed a high cholesterol diet or a standard diet supplemented with 2 forms of selenium.
• Assessment of selenium bioavailability from high-selenium spirulina subfractions in selenium-deficient rats.

3 preclinical trials:

• Assessment of the potential toxicological aspects of dietary exposure to silicon-rich spirulina in rats
• Dietary silicon-enriched spirulina improves early atherosclerosis markers in hamsters on a high-fat diet
• Dietary supplementation with silicon-enriched spirulina improves arterial remodeling and function in hypertensive rats

 1 PhD thesis:

• Potential effects and mechanisms of antioxidant and anti-inflammatory action of a nutritional intake of silicon-enriched spirulina

1 phase-III, randomized, double blind, placebo-controlled clinical trial at the Vascular Medicine department of Nîmes-Montpellier University Hospital:

• Assessment of the beneficial effects of silicon-enriched spirulina on cardiovascular disorders

To produce innovative fluorescent markers to improve medical diagnostic efficiency and meet the needs of the medical diagnostics industry.

We produce fluorescent markers derived from the extraction and purification of phycobiliproteins performed in our Montpellier laboratory.

We produce four types of phycobiliproteins, in precipitate and freeze-dried forms:

• Allophycocyanin (APC) and Crosslinked Allophycocyanin (APC-XL)
• C-Phycocyanin (C-PC)
• R-Phycoérythrin (R-PE)
• B-Phycoérythrin (B-PE)

Their purity and fluorescent properties allow very high detection sensitivity and they are also a non-polluting alternative to radioimmunoassays.

To cultivate, using environmentally sound and optimized methods, active ingredients derived from microalgae demonstrating efficacy recognized by health professionals. 

BIOASSIMIL™ products form a comprehensive range of natural, organic trace elements for nutraceutical use in human and animal health. They are made from entirely natural ingredients (without carriers) that are rich in metabolized trace elements and are produced in France according to our patented process.

Our R&D team working alongside the French National Institute for Health and Medical Research (INSERM), the French National Center for Scientific Research (CNRS) and the faculties of Medicine and Science at the University of Montpellier subject BIOASSIMIL™ trace elements to scientific studies to demonstrate their effectiveness.

Thanks to their excellent bioavailability and safety, BIOASSIMIL™ trace elements can be used to innovate formulations and market outstanding products that are valuable for a wide spectrum of natural health applications.